Urea: Moles to Grams

Convert moles of urea to the mass to weigh out, using 60.056 g/mol.

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Moles to grams for urea is a multiplication by 60.056 g/mol. A mole weighs 60.056 g, 100 mmol weighs 6.0056 g, 10 mmol weighs 0.60056 g and a millimole is 60.056 mg. Those four figures cover most of what gets weighed out in practice, and the table below extends them from a micromole up to ten moles.

The figure comes from the formula. Urea is 12.011 (C) + 4 × 1.008 (H) + 2 × 14.007 (N) + 15.999 (O), which is 60.056 g/mol, taking standard atomic weights, and every page here computes that sum rather than quoting it. Nitrogen makes up the largest share of the mass: 2 of the 8 atoms in a formula unit are nitrogen, and they account for 28.014 g of the 60.056 g, or 46.65% by mass. The derivation table below breaks the whole molecule down element by element.

Two habits make the weighed mass match the calculation. Weigh into a container you have tared rather than onto paper, because what stays behind on paper is a real loss — on a 100 mg weighing it is easily a percent. And when the target is under about 20 mg, weigh ten times that and dilute, since the absolute error of the balance does not shrink with the sample.

The nitrogen fertiliser with the highest nitrogen content, a skin humectant, and the compound the body uses to excrete nitrogen — reported as BUN. At 60.056 g/mol it is heavier than 3 of the 21 organic compounds covered here, and that ranking matters more than it looks: acetone has a molar mass of 58.08 g/mol, so a gram of it contains 3.4% more formula units than a gram of urea. Weigh by mass and you are not weighing equal amounts of substance.

Purity is the usual gap between the calculation and the balance. A reagent sold at 98% means 1.2011 g of a nominal 60.056 g is something else, so for exact work you divide the weighed mass by the assay figure on the certificate. For most purposes the difference is smaller than the error in reading the meniscus, but it is systematic rather than random, so it does not average out.

The formula

m = n × 60.056
n
The amount of urea you need, in moles
60.056
The molar mass of urea in g/mol, derived from its formula
m
The mass to weigh out, in grams

How it works, step by step

  1. Enter the amount you need, in moles.
  2. It is multiplied by 60.056 g/mol.
  3. The result is the mass to weigh out, also given in milligrams.
  4. Weigh into a tared container; anything left in the boat is a real loss from the amount you calculated.

Worked examples

5 mmol of urea in grams

5 mmol × 60.056 g/mol = 0.30028 g, which is 300.28 mg. Doubling the amount doubles the mass to 0.60056 g, because the relationship is a plain proportion once the molar mass is fixed.

250 mmol of urea in grams

250 mmol × 60.056 g/mol = 15.014 g, which is 15,014 mg. Doubling the amount doubles the mass to 30.028 g, because the relationship is a plain proportion once the molar mass is fixed.

2 mol of urea in grams

2 mol × 60.056 g/mol = 120.112 g, which is 120,112 mg. Doubling the amount doubles the mass to 240.224 g, because the relationship is a plain proportion once the molar mass is fixed.

How to read your score

0–0NothingZero moles is zero grams.
0–0.6006Milligram weighingUnder 600.56 mg, which is under 10 mmol of urea. A three-decimal balance is the minimum here.
0.6006–120.112Gram weighingFrom 600.56 mg up to 120.11 g: 10 mmol to 2 mol, the ordinary range for making up solutions.
120.112–—Bulk weighingMore than 120.11 g of urea. Buy by the labelled pack size and weigh the remainder.

Frequently asked questions

What is the molar mass of urea (CH4N2O)?

It is 60.056 g/mol. That is the sum of the standard atomic weights of every atom in the formula: 12.011 (C) + 4 × 1.008 (H) + 2 × 14.007 (N) + 15.999 (O). One mole of urea therefore weighs 60.056 g, and a gram of it is 16.651 mmol.

What percentage of urea is nitrogen?

46.65% by mass. Each formula unit contains 2 nitrogen atoms contributing 28.014 g of the 60.056 g total, so 100 g of urea contains 46.65 g of nitrogen and a kilogram contains 466.46 g of it.

How many grams is one mole of urea?

60.056 g, by definition of the molar mass. Two moles is 120.112 g and half a mole is 30.028 g.

How many grams is 0.1 mol, and how many milligrams is 1 mmol?

0.1 mol of urea is 6.0056 g. One millimole is 60.056 mg and one micromole is 60.056 µg, which is the range most bench work sits in.

How do I weigh out an amount too small for my balance?

Weigh a larger mass and dilute it. To get 0.6006 mg of urea, weigh 6.006 mg into 100 mL, then take 10 mL of that: the absolute error of the balance stays the same while the amount delivered falls by a factor of ten.

Should I use the hydrate or the anhydrous molar mass?

This page is the anhydrous form, CH4N2O, at 60.056 g/mol. If your jar is the other form the molar mass differs and so will every mass you weigh, so check the label before using the figure. Salts that are sold as hydrates weigh more per mole because the water is part of the crystal.

Moles to grams reference for urea

How the molar mass of urea is arrived at
ElementAtomsAtomic weightContribution (g/mol)By mass
Nitrogen (N)214.00728.01446.65%
Oxygen (O)115.99915.99926.64%
Carbon (C)112.01112.01120%
Hydrogen (H)41.0084.0326.714%
Total — one mole of urea60.056100%

Standard atomic weights, IUPAC 2021. The contribution column is atoms × atomic weight, and the total is the molar mass this page uses: 60.056 g/mol.

Grams of urea to weigh for a given number of moles
WantedWeigh (g)Weigh (mg)With 2% over (g)
1 µmol0.0000600.0600560.000061
10 µmol0.000600560.600560.000612571
100 µmol0.00600566.00560.00612571
1 mmol0.06005660.0560.0612571
10 mmol0.60056600.560.612571
50 mmol3.00283002.83.06286
100 mmol6.00566005.66.12571
250 mmol15.01415,01415.3143
500 mmol30.02830,02830.6286
750 mmol45.04245,04245.9428
1 mol60.05660,05661.2571
2 mol120.112120,112122.514
5 mol300.28300,280306.286
10 mol600.56600,560612.571

Weigh is the amount multiplied by 60.056 g/mol. The last column carries a 2% allowance, which is what you take when some of the solid will be left in the weighing boat.

Urea among other organic compounds, by molar mass
CompoundFormulaMolar mass (g/mol)Millimoles in 1 g
MethanolCH4O32.04231.209
EthanolC2H6O46.06921.707
AcetoneC3H6O58.0817.218
Urea (this page)CH4N2O60.05616.651
Isopropyl alcoholC3H8O60.09616.64
Ethylene glycolC2H6O262.06816.111
GlycineC2H5NO275.06713.321

Ordered by molar mass. The last column is 1000/M, which is the number a weighed gram actually gives you.

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